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The author was recently asked by a hospice organization, of which he is a board membe...
Study objectives: To review the use of incarceration for noncompliance with tuberculo...
Objectives: Foreign body aspiration into the lower airway in adults is uncommon. We d...
Some patients with chest wall diseases (CWD) without respiratory failure manifest imp...
A 20-year-old Vietnamese man was admitted to the hospital with fever and pharyngitis....
When Franklin Roosevelt entered his fourth term as President of the United States in ...
Study objectives: To compare the costs and effectiveness of directly observed therapy...
Silicone and metal stents are available for the treatment of malignant bronchial sten...
Study objective: To determine the effect of exposure to cigarette smoke on the elasto...
Lemierre's syndrome is an anaerobic sepsis occurring after oropharyngeal infection in...
Background: The effects of regular inhaled [Beta]-agonist treatment on lung function ...
This prospective study was conducted to describe the signs on transesophageal echocar...
To investigate the effects of the autonomic nervous system on control of breathing, t...
Clinically apparent involvement of the nervous system occurs in a relatively small nu...
A 41-year-old woman had progressive shortness of breath. Cerebrotendinous xanthomatos...
Study objectives: This study was designed to evaluate the effects of age on bronchodi...
Objectives: To elucidate whether atherosclerotic aortic plaque detected by transesoph...
Study objectives: To investigate the etiology of posthyperventilation (post-HV) hypox...
It has been suggested that T3/N0-1/M0 non-small cell lung cancer should be classified...
The diagnosis and treatment of pneumothorax in patients with complex cystic lung dise...
Despite the increasing use of dry powder formulations in the ambulatory setting, ther...
Objective: To identify lifestyle, anthropometric, biochemical, and clinical character...
Objective: To determine the levels of glutathione and cysteine in patients with ARDS ...
Pneumothorax is a rare manifestation of sarcoidosis, occurring usually late in the co...
Did I miss something? When did we, the trainers of new physicians, begin to train phy...
Study objectives: To determine if treatment with low-dose methotrexate spares oral st...
Study objectives: To confirm that a newly drafted treadmill exercise protocol designe...
Objective: To determine whether a rapid qualitative assay for the detection of circul...
It is difficult to identify characteristics of patients with unstable angina that are...
The concept that inflammation is a significant pathogenic event in bronchial asthma i...
Study objective: To compare the efficacy and safety of a double-strength formulation ...
Study objective: To evaluate a newly developed laser monitor in the measurement of po...
Objective: To determine the incidence of and risk factors for unexplained paroxysmal ...
We report the first example of smooth-muscle proliferations occurring in an allograft...
Asthma has been a major disease focus for the past 7 years due to the increasing morb...
Objectives: To determine if renal dose dopamine (3 [micro]g/kg/min) alters the heart ...
Study objective: A technique for assessing expiratory muscle strength is the measurem...
Objective: To examine medical outcomes associated with reintubation for extubation fa...
Background: Small cell lung cancer (SCLC) cells express and secrete gastrin-releasing...
Although recurrent, massive pleural effusions frequently are associated with malignan...
In 1987, based on a steady annual decline in the number of tuberculosis (TB) cases in...
Objectives: To evaluate the relationships between airway subepithelial collagen depos...
Study objectives: To investigate the short-term effects of noninvasive ventilatory su...
Objectives: Sedation and ventilation overnight after cardiac surgery is common practi...
Morton E. Tavel, MD, FCCP; Lameh Fananapazir, MD; and Nora F. Goldschlager, MD (CH...
In the study by Green RJ, et al titled "Pulmonary Capillaritis and Alveolar Hemorrhag...
Through the first half of this century, artificial pneumothorax (AP) had been the pre...
Study objective: The lower limit for the baseline value to initiate methacholine bron...
Objectives: Most patients with severe pulmonary emphysema referred for lung volume re...
Objective: To determine whether emergency rigid bronchoscopic intervention, including...
A 41-year-old man was referred for evaluation of an abnormal chest roentgenogram. At ...
In the Executive Summary "From Bench to Bedside: The Future of Sepsis Research" (Dell...
Extracellular superoxide dismutase (EC-SOD) is the major extracellular antioxidant en...
To many investigators, the concept of gene therapy involves the permanent transfer of...
Fetal lung secretes into the future airspaces fluid that arises from a continuous act...
The alveolar epithelium is a critical element in response to acute lung injury. Recen...
The concept and use of an airway exchange catheter (AEC) as an additional safety meas...
Study objective: To assess the potential utility of specific airway conductance (sGaw...
Objective: Pulmonary cytologic specimens reported as "suspicious for malignancy" pose...
Study objectives: To update our database, reporting changes in the results of weaning...
Recommendations for classifying regional lymph node stations for lung cancer staging ...
Drug-induced pneumonitis is an uncommon complication of nonsteroidal anti-inflammator...
Over the past 8 years, a tremendous interest has grown in identifying the genetics of...
Neutrophil (polymorphonuclear leukocyte [PMN])-dominated inflammation in the lung con...
The interface between the lung and the atmosphere poses major challenges for all air-...
The liver represents an important target organ for gene therapy because there are a l...
It has been a little over 10 years since the last revision of the staging system for ...
Study Objective: Increasing evidence indicates that routine preoperative diagnostic s...
Twenty-one patients with malignant pleural effusion (MPE) were prospectively entered ...
Viral vectors, although efficient for the transfection of the cystic fibrosis gene (C...
Lung development is regulated by a number of genetic and epigenetic factors including...
Objective: Sleep-disordered breathing (SDB) is common in congestive heart failure. Wh...
Study objectives: Scintigraphic prediction of the residual pulmonary function followi...
Study objectives: To determine whether bone imaging with [sup.99m]Tc methylene diphos...
To assess the prognostic performance of general severity systems (APACHE II [acute ph...
We conducted a longitudinal study to determine the annual rate decline in pulmonary f...
A 53-year-old man was admitted to the hospital for management of pneumonia and a gian...
Two common N-terminal polymorphisms have been described in the [Beta.sub.2]-adrenocep...
Genetic factors have been shown to promote the development of pulmonary hypertension ...
Novel treatments for acquired diseases may be accomplished by the transfer of therape...
The idea using of gene therapy began with the straight-forward paradigm of treating g...
Study objective: To determine the sleep/wake habits of patients diagnosed as having o...
Study objectives: To determine the optimal treatment of empyema thoracis (within the ...
Background: Recent findings have demonstrated a high frequency of activated protein C...
Key words: chronic obstructive pulmonary disease; hypercapnia; hypoxemia; intermitten...
Objective: To demonstrate that a consensus approach for combining prediction equation...
Bronchiolitis obliterans organizing pneumonia (BOOP) is an uncommon but increasingly ...
Hereditary hemorrhagic telangiectasia (HHT) or Rendu-Osler-Weber disease is an autoso...
Expression of the gene-encoding surfactant protein-A (SP-A) is lung-specific, occurs ...
Carboxypeptidase M (CPM) is a cell surface peptidase which hydrolyzes bioactive pepti...
Background: Upper airway inflammation is present in patients with obstructive sleep a...
Study objectives: We developed a symptom-based measure of severity for chronic lung d...
Study objectives: The objective of this study was to determine the impact of the timi...
A 62-year-old man was admitted to the hospital with progressive shortness of breath a...
Intravenous haloperidol is recommended as the drug of choice to treat delirium in ICU...
Primary pulmonary hypertension (PPH) is a progressive disease that usually leads to d...
Interferon-gamma (IFN) and tumor necrosis factor (TNF) have been demonstrated to be c...
Human neutrophil elastase is thought to be involved in lung diseases such as emphysem...
I would like to first thank the Aspen conference organizers. This was my first trip t...
Study objective: Nebulizer systems used to generate therapeutic aerosols vary in thei...
Objective: This study was designed (1) to investigate the effects of normothermic and...
The approach to the diagnosis and management of patients with diffuse infiltrative lu...
Background: Mouse/human chimeric antibody Z2D3 identifies an antigen produced exclusi...
A 31-year-old man presented with fever, a 10- to 20-lb weight loss over 4 months, and...
Patients with acute lupus pneumonitis (ALP) usually have hypoxemia, patchy infiltrate...
It is becoming clear that the information obtained from measurement of gene expressio...
Platelet-derived growth factor (PDGF) has been recognized as a competence factor for ...
Prostacyclin synthase (PGIS) is the final committed enzymatic step in the pathway of ...
Primary care physicians can do the work of specialists. Nurse practitioners can do th...
Background: In comparison to [Beta]-agonist drugs, which are the primary bronchodilat...
Study objectives and patients: Pulmonary hypertension (PH) is common in COPD and may ...
Background: Development and progression of human malignancies involve multiple geneti...
A 55-year-old woman with a previous history of carcinoma of the breast is admitted fo...
Formation of the vertebrate lung requires an orderly array of complex cell to cell an...
Liquid secretion by the lung epithelium, which is an important determinant of lung gr...
Pulmonary surfactant is the mixture of lipids and proteins needed to reduce alveolar ...
No disease in thoracic medicine or surgery has been known longer than empyema. Hippoc...
Study objective: Systemic administration of [Beta]-agonist and anticholinergic drugs ...
The purpose of this study was to investigate the possible use of integrated surface e...
Study objectives: It has been suggested that noninvasive mechanical ventilation (NIMV...
Gamma-delta ([Gamma]/[Delta]) T cells are thought to represent the first line of defe...
Background: Inhaled nitric oxide (NO) at levels between 5 and 80 ppm has been used ex...
Positional cloning is used to identify defective genes causing inherited diseases bas...
The homeodomain thyroid transcription factor TTF-1 is a lung- and thyroid-enriched pr...
Noncompliance with self-administered multidrug tuberculosis treatment regimens is com...
Study objectives: Contrast transthoracic echocardiography (TTE) is currently used to ...
Objective: To determine the frequency of acute postoperative atelectasis in patients ...
Study objectives: The function of jet nebulizers has been measured traditionally by g...
(CHEST 1997; 111:1427-28) The preceding essay "Asbestos-Related Disorders: A Reali...
We present a case of recurrent alveolar proteinosis following double lung transplanta...
Study objectives: (1) To assess the utility of a single sputum specimen in the evalua...
Study objectives: To determine the risk factors and frequency of intracranial hemorrh...
A simple, accurate, and noninvasive method of cardiac output measurement can be an ex...
Study objective: We hypothesized that the continuous gas flow administration delivere...
Pentoxifylline (PTX) has been shown to reduce sepsis-induced neutrophil sequestration...
During a 5-year study period, we diagnosed pulmonary tuberculosis in two (2%) of 94 l...
In this issue of CHEST (see page 1162), Kritski and colleagues present a short but pr...
Objective: To investigate the influence of empiric treatments prior to fiberoptic bro...
Purpose: The purpose of this investigation is to determine the prevalence of acute pu...
The pathogenesis of hyperlactatemia during sepsis is poorly understood. We have previ...
Aortic root abscess is a common complication of aortic valve endocarditis. However, a...
A previously unreported case of small-vessel myocardial vasculitis presenting as rest...
Directly observed therapy (DOT) has been the most significant advance in the treatmen...
Study objectives: In patients with HIV infection, serum lactate dehydrogenase (LDH) l...
Study objective: Systemic inflammatory response syndrome (SIRS) and infections are fr...
(CHEST 1997, 111:1439-41) A 77-year-old man with a history of peripheral vascular dis...
A View From the Community Hospital After a patient's initial evaluation, the physi...
Objective: Pneumocystis carinii pneumonia is the most common and serious of the pulmo...
Lung epithelial permeability of asthmatic patients has been reported to be similar or...
Study objective: To assess whether pressure support ventilation (PSV) could be used a...
(CHEST 1997; 111:1389-1402) Key words: asthma; chronic cough; gastroesophageal reflux...
(CHEST 1997; 111:1442-45) A 42-year-old woman complained of cough of 1 year's duratio...
"A vague idea of the benefit of inhalation in the treatment of diseases of the air pa...
Background and objectives: Continuous administration of aerosolized [[Beta].sub.2]-ag...
Study objective: This study aimed to evaluate the effects of nasal continuous positiv...
A postmyocardial infarction left ventricular pseudoaneurysm occurs when a rupture of ...
A case of amiodarone pulmonary toxicity (APT) occurring within days of the start of t...
Pericardial fluid, normally measuring 15-35 mL, is mainly an ultrafiltrate of plasma,...
The use of inhaled antibiotics in the treatment of cystic fibrosis has become widespr...
Study objective: To determine the within-subject variability and to estimate the quan...
Objective: To examine the relationship between age and mortality in ARDS patients and...
(CHEST 1997; 111:1410-13) Key words: deep vein thrombosis; diagnosis; mortality; natu...
Thoracic endometriosis is a rare disorder. We report a case of a 26-year-old woman wi...
Lactic acidosis is characteristic of all forms of shock, including that due to system...
Study objectives: To determine an effective means of improving compliance with nasal ...
Objective: To update the epidemic curves for lung cancer in the United States by gend...
Digital subtraction angiography is an indispensable complement to cut film studies fo...
Occult carcinomas of the lung are a subpopulation defined as carcinomas diagnosed by ...
Study objectives: Electrical impedance tomography (KIT) offers the possibility to stu...
Objectives of the study: Pilot study to assess high-dose rate (HDR) brachytherapy as ...
Independent lung ventilation with two ventilators is sometimes used in the management...
Study objective: Risk factors associated with treatment failure and multidrug-resista...
Study objective: To define the most severe form of postlobectomy atelectasis and dete...
Background: Following tracheal intubation, a small proportion of patients develop lar...
(CHEST 1997; 111:1424-26) Millions of workers have had occupational exposure to as...
A case is presented in which amiodarone was administered to suppress paroxysmal atria...
Silicosis is a fibrotic lung disease that results from exposure to crystalline silica...
Several methods are used for the assessment of airway responsiveness.[1] One well-acc...
Experimental studies in animals and observations in patients demonstrate that applica...
Lung malignancies represent the leading cause of cancer mortality in the United State...
Lung volume reduction surgery has been utilized extensively over the last 2 years to ...
Although most patients are admitted to the medical ICU (MICU) for conditions other th...
Members of a family have been investigated because of three sudden deaths among them....
Premenstrual asthma (PMA) is a recognized clinical entity. The question of whether PM...
Approximately 5 to 6% of patients presenting with hemoptysis and a normal chest radio...
It is becoming widely accepted that pulmonary rehabilitation has an important role in...
Patients with severe kyphoscoliosis can develop fatal respiratory failure. This proce...
Clinicians face daily decisions regarding diagnostic testing. The appropriate selecti...
During the invasion and metastasis formation process, tumor cells confront a variety ...
Progressive obstructive pulmonary disease in most patients with cystic fibrosis (CF) ...
In the last decade, most comparative ICU performance evaluations have concentrated on...
(CHEST 1997; 111:1112-14) A 53-year-old woman with severe parkinsonism (Parkinson'...
Fibrosing mediastinitis and sclerosing cervicitis are fibrosclerotic disorders akin t...
More or Less? Obesity is one of the most frequently found markers of health risk i...
Obesity is a common problem in the United States with a variety of effects on the res...
Although patients with acute inferior wall myocardial infarction who demonstrate ST-s...
CHEST 1997; 111:1115-16 You are asked to evaluate a 23-year-old woman who has had ...
Michael A. Chizner Ed. Cedar Grove, New Jersey: Laennec Publishing Inc., 1996, 1,526 ...
In this issue of CHEST (see page 1000), Payen and coworkers describe their experience...